Everything about ceesdekker.net
Everything about ceesdekker.net
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Rotary motion of DNA rotors on nanopores. Prime row: Uncooked online video with the Cy5 channel of each and every rotor. Center row: corresponding one-particle localization success of both of those finishes with the DNA rotors. The posture of the present frame is marked as orange and blue dots, and the trajectory of The ten frames ahead of the current frame is revealed as sound strains.
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Sculpting nano-electrodes using a transmission electron beam for electrical and geometrical characterization of nanoparticles.
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Our analysis ranges from your biophysics of DNA to synthetic cells and past. Make sure you have a look beneath in the spectrum of our present tasks.
All parameters were being exactly the same for each panel On this movie, aside from the Original placement of your 6hb rod (shown in blue) around the nanopore. Simulations that terminated early resulting from translocation with the rod in the pore are marked by a gray history.
2011, to start with in vitro measurements of transportation throughout one biomimetic nuclear pore complicated; advancement of multiplexed magnetic tweezers for kilo-molecule experiments; and settled the mechanism of homology recognition in DNA homologous recombination
The rotors harness Electricity from a nanoscale water and ion move that may be produced by a static chemical or electrochemical prospective gradient within the nanopore, which are founded by way of a salt gradient or applied voltage, respectively. These synthetic nanoengines self-Arrange and operate autonomously in physiological ailments, suggesting approaches to constructing Electricity-transducing motors at nanoscale interfaces.
Bulk-surface area coupling identifies the mechanistic link involving Min-protein styles in vivo As well as in vitro
[14] In 2005 Dekker grew to become linked to Netherlands-vast conversations about Intelligent Structure, a movement that he has due to the fact Obviously ceesdekker distanced himself from. Dekker advocates that science and faith aren't in opposition but might be harmonized.
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Developments in nanotechnology while in the nineties designed making Digital equipment from one molecules a risk. Cees Dekker recounts how his workforce established a home-temperature transistor based on a single carbon nanotube.
2004, discovery of latest physics in translocation of DNA via nanopores; first experimental analyze of ions conduction in nanofluidic channels; 1st electrochemistry with person one-wall carbon nanotubes; STM detection and control of phonons in carbon nanotubes; to start with electrical docking of microtubules on kinesin-coated nanostructures; 1st biophysics characterization from the mechanical Attributes of double-stranded RNA; and 1st single-molecule review of DNA translocation by a restriction-modification enzyme.